Case of familial hyperlipoproteinemia type III hypertriglyceridemia induced acute pancreatitis: Role for outpatient apheresis maintenance therapy.

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Term Occurence Count Dictionary
Insulin 3 endocrinologydiseasesdrugs
diabetes mellitus 2 endocrinologydiseases
gemfibrozil 1 endocrinologydiseasesdrugs
hyperglycemia 1 endocrinologydiseases
hypothyroidism 1 endocrinologydiseases
atorvastatin 4 endocrinologydiseasesdrugs
fenofibrate 4 endocrinologydiseasesdrugs
hypertriglyceridemia 2 endocrinologydiseases
lactic acidosis 1 endocrinologydiseases
niacin 2 endocrinologydiseasesdrugs

Graph of close proximity drug and disease terms (within 200 characters).

Note: If this graph is empty, then there are no terms that meet the proximity constraint.

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Select Drug Character Offset Drug Term Instance
Insulin 9379 Intravenous insulin has been shown to be more effective than subcutaneous insulin in managing HTGP[[25]]. Insulin increases lipoprotein lipase which in turn accelerates chylomicron and VLDL metabolism to glycerol and
Insulin 11422 decrease in HTG levels. Apheresis within 48 h associated with better outcomes[[15]]Furuya et al[[15]], 2002 Insulin Intravenous regular insulin drip (0.1 to 0.3 units/kg/h). Goal is TGH < 500. Used alone or in combination
Insulin 13985 diagnosisAbdominal CT scan showed moderate fat stranding around the pancreas and stable pseudocyst.Treatment Insulin , apheresis, atorvastatin 80 mg daily, fenofibrate 200 mg and omega-3 polyunsaturated fatty acids.Related
atorvastatin 4417 40-year-old Caucasian male with a past medical history significant for hyperlipoproteinemia type III (on atorvastatin 80 mg daily, fenofibrate 200 mg daily and omega-3 polyunsaturated fatty acids), coronary artery disease
atorvastatin 6125 hydrochlorothiazide 12.5 mg daily, Plavix 75 mg daily, aspirin 325 mg daily, metoprolol tartrate 50 mg BID, atorvastatin 80 mg daily, fenofibrate 200 mg and omega-3 polyunsaturated fatty acids. Twelve mo post-discharge course
atorvastatin 13053 40-year-old Caucasian male with a past medical history significant for hyperlipoproteinemia type III (on atorvastatin 80 mg daily, fenofibrate 200 mg daily and omega-3 polyunsaturated fatty acids), coronary artery disease
atorvastatin 14005 showed moderate fat stranding around the pancreas and stable pseudocyst.TreatmentInsulin, apheresis, atorvastatin 80 mg daily, fenofibrate 200 mg and omega-3 polyunsaturated fatty acids.Related reportsThere are a number
fenofibrate 4443 a past medical history significant for hyperlipoproteinemia type III (on atorvastatin 80 mg daily, fenofibrate 200 mg daily and omega-3 polyunsaturated fatty acids), coronary artery disease status post 3-vessel
fenofibrate 6151 Plavix 75 mg daily, aspirin 325 mg daily, metoprolol tartrate 50 mg BID, atorvastatin 80 mg daily, fenofibrate 200 mg and omega-3 polyunsaturated fatty acids. Twelve mo post-discharge course was remarkable for a
fenofibrate 13079 a past medical history significant for hyperlipoproteinemia type III (on atorvastatin 80 mg daily, fenofibrate 200 mg daily and omega-3 polyunsaturated fatty acids), coronary artery disease status post 3-vessel
fenofibrate 14031 stranding around the pancreas and stable pseudocyst.TreatmentInsulin, apheresis, atorvastatin 80 mg daily, fenofibrate 200 mg and omega-3 polyunsaturated fatty acids.Related reportsThere are a number of case reports in
gemfibrozil 10707 when combined with lipid lowering agents[[14]]Tsuang et al[[14]], 2009Lipid lowering agentsFibrates ( gemfibrozil 600 mg twice daily), niacin, N-3 fatty acids, statinsFirst line in HTGTriglyceride level lowered about
niacin 10740 agents[[14]]Tsuang et al[[14]], 2009Lipid lowering agentsFibrates (gemfibrozil 600 mg twice daily), niacin , N-3 fatty acids, statinsFirst line in HTGTriglyceride level lowered about 60% by fibrates, about 50%
niacin 10852 fatty acids, statinsFirst line in HTGTriglyceride level lowered about 60% by fibrates, about 50% by niacin , about 45% by omega-3 fatty acids[[14]]Tsuang et al[[14]], 2009Adjuvant therapy in HTGPApheresisTherapeutic
Select Disease Character Offset Disease Term Instance
diabetes mellitus 4628 disease status post 3-vessel coronary artery bypass graft, peripheral vascular disease, hypertension, diabetes mellitus (DM) type 2, and one reported episode of acute pancreatitis in the past presented with epigastric pain,
diabetes mellitus 13264 disease status post 3-vessel coronary artery bypass graft, peripheral vascular disease, hypertension, diabetes mellitus type 2, and one reported episode of acute pancreatitis in the past presented with epigastric pain, nausea
hyperglycemia 11699 tolerate apheresisIntravenous insulin is more effective than subcutaneous[[16]]Berger et al[[16]], 2001 hyperglycemia > 500Effective in lowering triglyceride levelsHeparinCombined with insulin. Subcutaneous heparin 500
hypertriglyceridemia 87 Title: World Journal of GastroenterologyCase of familial hyperlipoproteinemia type III hypertriglyceridemia induced acute pancreatitis: Role for outpatient apheresis maintenance therapyMohannad Abou SalehDepartment
hypertriglyceridemia 14889 apheresis in preventing recurrent attacks of HTGP.Peer-reviewThis is a nice case report on a timely topic: hypertriglyceridemia -induced acute pancreatitis and role for outpatient apheresis maintenance therapy. This manuscript is
hypothyroidism 7935 to accumulation of VLDL and chylomicrons leading to HTG. Secondary HTG is caused by DM, alcoholism, hypothyroidism , pregnancy, and certain medications such as thiazides, beta blockers, corticosteroids, isotretinoin,
lactic acidosis 8673 lower triglyceride level > 10 g/L and improve signs of severe inflammation such as hypocalcemia and lactic acidosis . One study reported (average TG of 14.06 g/L) a 41% decrease in TGs after one session of plasma exchange[[17]].

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