Influence of uncontrolled diabetes mellitus on periodontal tissues during orthodontic tooth movement: a systematic review of animal studies.

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Term Occurence Count Dictionary
Insulin 3 endocrinologydiseasesdrugs
diabetes mellitus 4 endocrinologydiseases

Graph of close proximity drug and disease terms (within 200 characters).

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Select Drug Character Offset Drug Term Instance
Insulin 8356 (8)44 days120 ± 15 g closed-coil spring between the upper molars for 1 weekDM decreased bone remodeling during OTM. Insulin prevented effects of DM on the alveolar bone[[20]]Zhang et al. 201148 Sprague–Dawley ratsGroup 1:
Insulin 9269 miniscrew and the maxillary molar for 2 weeksDM reduced rate of OTM and decreased bone resorption. Insulin reduced adverse effects of DM on OTM[[15]]DM diabetes mellitus, LLLT low-level laser therapy, OTM orthodontic
Insulin 11466 Furthermore, DM decreased rate of OTM in one study [[15]], but in another study, DM accelerated OTM [[16]]. Insulin diminished bone resorption in two studies [[15], [20]].Results of quality assessmentAs shown in Table 3,
Select Disease Character Offset Disease Term Instance
diabetes mellitus 57 Title: Progress in OrthodonticsInfluence of uncontrolled diabetes mellitus on periodontal tissues during orthodontic tooth movement: a systematic review of animal studiesShariq
diabetes mellitus 5831 conducted via PubMed/Medline, using the Medical Subject Headings (MeSH) terms “bone remodeling,” “ diabetes mellitus ,” “orthodontics” and “tooth movement” for studies published between January 2000 and August
diabetes mellitus 6651 literature from PubMed for this studyMeSH termsInclusion criteriaExclusion criteria“Bone remodeling,” “ diabetes mellitus ,” “orthodontics,” and “tooth movement”• Prospective clinical trials• Animal studies•
diabetes mellitus 9322 reduced rate of OTM and decreased bone resorption. Insulin reduced adverse effects of DM on OTM[[15]]DM diabetes mellitus , LLLT low-level laser therapy, OTM orthodontic tooth movement, TIMP tissue inhibitor of metalloproteinaseResultsSearch

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