Functional Foods and Lifestyle Approaches for Diabetes Prevention and Management.

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Term Occurence Count Dictionary
alpha-linolenic acid 1 endocrinologydiseasesdrugs
diabetes mellitus 3 endocrinologydiseases
glucose intolerance 1 endocrinologydiseases
hyperinsulinemia 1 endocrinologydiseases
polycystic ovary syndrome 1 endocrinologydiseases
type 2 diabetes mellitus 3 endocrinologydiseases
cortisol 4 endocrinologydiseasesdrugs
hypoglycemia 1 endocrinologydiseases
metabolic syndrome 4 endocrinologydiseases
obesity 7 endocrinologydiseases

Graph of close proximity drug and disease terms (within 200 characters).

Note: If this graph is empty, then there are no terms that meet the proximity constraint.

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Select Drug Character Offset Drug Term Instance
alpha-linolenic acid 10356 monounsaturated fatty acids (MUFA) such as oleic acid in olive oil, omega-3 polyunsaturated fatty acids (e.g., alpha-linolenic acid ) found in tree nuts such as walnuts [[12]], eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)
cortisol 22363 mediators [[65],[66],[67],[68],[69]].The mechanisms associated with glucocorticoid metabolism, particularly cortisol regulation of glucose homeostasis, have been described in mediating the association between obesity
cortisol 22827 Specific phenolics, especially ECGC have demonstrated ability as a highly efficacious inhibitor of the cortisol producing enzyme 11β-HSD1 in experimental model systems [[72]], and consumption of phenolic-rich cocoa
cortisol 22965 experimental model systems [[72]], and consumption of phenolic-rich cocoa and pomegranate regulate cortisol metabolism in clinically obese and overweight populations [[73],[74]]. The potential mechanism of inhibition
cortisol 23321 potential role of phenolics as novel inhibitors of human 11β-HSD1 and suggest an association between cortisol , glucose, insulin, blood pressure, and lipid profile which may be important in our understanding by
Select Disease Character Offset Disease Term Instance
diabetes mellitus 1109 associated with physiological health benefits for preventing and managing chronic diseases, such as type 2 diabetes mellitus (T2DM). A regular consumption of functional foods may be associated with enhanced anti-oxidant, anti-inflammatory,
diabetes mellitus 2728 provide additional benefits in such an approach.1. Overview and BackgroundThe prevalence of type 2 diabetes mellitus (T2DM) is increasing at an alarming rate worldwide, causing a significant increase in premature mortality,
diabetes mellitus 44790 intensity training; HbA1c, glycosylated hemoglobin A1c; HOMA, homeostatic model assessment; T2DM, type 2 diabetes mellitus
glucose intolerance 14638 shown up to 58% reduction of the T2DM incidence rate in high risk individuals, especially those with glucose intolerance from different countries including multiethnic American [[3]], Finnish [[4]], Chinese [[5]], and Indian
hyperinsulinemia 22516 described in mediating the association between obesity and cardiometabolic risk factors, including hyperinsulinemia and insulin resistance [[70]]. For example, increased 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1)
hypoglycemia 40009 Awareness Restoration Training (DAFNE-HART) participants along with diabetes education led to changes in hypoglycemia awareness [[135]].Currently, nutrition education relies heavily on teaching caloric and carbohydrate
metabolic syndrome 8774 high-risk individuals, including impaired fasting glucose (IFG), impaired glucose tolerance (IGT) and metabolic syndrome , associated with MD consumption [[11],[25]]. For example, MD compared with control diets has been shown
metabolic syndrome 13174 virgin olive oil—were also reviewed elsewhere for their partial effective role on aspects of the metabolic syndrome [[40]]. Whereas, non-flavonoid polyphenolic compound hydroxytyrosol, the main polyphenol of olive oil,
metabolic syndrome 19818 than a single component prevention program. For example, a multi-component intervention in people with metabolic syndrome , which combined hypocaloric MD with 12 weeks of moderate-to-heavy exercise training, was more effective
metabolic syndrome 20036 effective than MD alone in enhancing physical aspects (weight loss, physical fitness, and improvement of metabolic syndrome risk factors) and mental domains of health-related quality of life measures (vitality, general physical
obesity 8032 play an important role in maintaining wellness, and contribute to preventing cancer, depression, T2DM, obesity , asthma, and cognitive decline [[23],[24]]. Specific to T2DM, reported actions of such foods include
obesity 9627 score, and a 136-item food frequency questionnaire) [[16]] reduces incidence rates irrespectively of obesity changes (indicated by Body Mass Index; BMI) during 9.5-year follow-up, suggesting that MD may attenuate
obesity 9762 Mass Index; BMI) during 9.5-year follow-up, suggesting that MD may attenuate the adverse effects of obesity on the risk of T2DM [[29]]. Indeed, MD is not a calorically-restricting diet, since some of its central
obesity 22464 cortisol regulation of glucose homeostasis, have been described in mediating the association between obesity and cardiometabolic risk factors, including hyperinsulinemia and insulin resistance [[70]]. For example,
obesity 33708 identified to interfere with dietary response and they could be used to predict the interplay between obesity and dietary responses [[95]]. Since these studies have only used animal models as study targets, human
obesity 34415 kg/m2) patients with co-morbidities such as T2DM, hypertension, dyslipidemia, obstructive sleep apnea, obesity hypoventilation, gastroesophageal influx disease, asthma, venous stasis, polycystic ovary syndrome,
obesity 37746 further enhanced using herbs and functional foods, especially given their already common use among obesity patients. However, issues related to safety and under-reported use of such foods need to be carefully
polycystic ovary syndrome 34496 obstructive sleep apnea, obesity hypoventilation, gastroesophageal influx disease, asthma, venous stasis, polycystic ovary syndrome , and pseudotumor cerebri [[96]]. Some even consider it as a standard option for obese T2DM patients
type 2 diabetes mellitus 1102 associated with physiological health benefits for preventing and managing chronic diseases, such as type 2 diabetes mellitus (T2DM). A regular consumption of functional foods may be associated with enhanced anti-oxidant, anti-inflammatory,
type 2 diabetes mellitus 2721 foods may provide additional benefits in such an approach.1. Overview and BackgroundThe prevalence of type 2 diabetes mellitus (T2DM) is increasing at an alarming rate worldwide, causing a significant increase in premature mortality,
type 2 diabetes mellitus 44783 moderate intensity training; HbA1c, glycosylated hemoglobin A1c; HOMA, homeostatic model assessment; T2DM, type 2 diabetes mellitus

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