Nuts and Dried Fruits: An Update of Their Beneficial Effects on Type 2 Diabetes.

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Term Occurence Count Dictionary
diabetes mellitus 1 endocrinologydiseases
hyperlipidemia 1 endocrinologydiseases
niacin 1 endocrinologydiseasesdrugs
Insulin 8 endocrinologydiseasesdrugs
hyperglycemia 3 endocrinologydiseases
hyperinsulinemia 1 endocrinologydiseases
metabolic syndrome 4 endocrinologydiseases
metformin 1 endocrinologydiseasesdrugs
obesity 2 endocrinologydiseases
type 2 diabetes mellitus 1 endocrinologydiseases

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Select Drug Character Offset Drug Term Instance
Insulin 31487 known about raisins.5. Potential Mechanisms Linking Nut and Dried Fruit Consumption to Glucose and Insulin Metabolism5.1. Nut- and Dried Fruit-Related Nutrients and Their Role in Glucose and Insulin MetabolismFiber
Insulin 31579 Glucose and Insulin Metabolism5.1. Nut- and Dried Fruit-Related Nutrients and Their Role in Glucose and Insulin MetabolismFiber Content in Nuts and Dried FruitsBoth nuts and DFs are high in dietary fiber [[9]]. Diets
Insulin 49932 outcomes.First Author (Year) [Reference]Nut (Study Length)Animal Model UsedControlInterventionGlucose and Insulin Metabolism EffectsOther OutcomesBilbis, L.S.; et al. (2002) [[25]]Aqueous extract of peanut (21 days)Alloxan-induced
Insulin 56419 Type of Subject (Age in Years)Type of Nut (Study Design)Control GroupIntervention GroupGlucose and Insulin Metabolism OutcomesOther OutcomesJenkins, D.J.; et al. (2006) [[69]]15 (7/8) Healthy subjects (26.3
Insulin 60759 in Years)Nut Study Design (Length of the Intervention)Control GroupIntervention Group(s)Glucose and Insulin Metabolism OutcomesOther OutcomesLovejoy, J.C.; et al. (2002) [[79]]30 (13/17)T2D subjects(mean ± SEM:
Insulin 65374 lower CHO(45 E%), higher fat (35 E%) dietWalnut-enriched diet: high fat (35 E%), lower CHO (45 E%) diet. Insulin sensitivity and CRP levels improved after walnut-rich dietTG decreased in all study arms at 6 months.
Insulin 66682 Type of Subject (Age in Years)Dried Fruit (Study Design)Control GroupIntervention Group(s)Glucose and Insulin Metabolism OutcomesOther OutcomesRasmussen, O.; et al. (1989) [[109]]20 (9/11)Healthy (n = 11) and T2D
Insulin 70000 (Age in Years)Study Design (Length of the Intervention)Control GroupIntervention Group(s)Glucose and Insulin Metabolism OutcomesOther OutcomesPuglisi, M.J.; et al. (2008) [[115]]34 (17/17 PM)Healthy(range: 50–70)RaisinParallel
metformin 15859 myoblast C2C12 muscle cells in the absence of insulin [[40]] via a mechanism which is highly analogous to metformin . Importantly, quercetin seems to be as effective as or more effective than resveratrol in attenuating
niacin 5281 Dried FruitsNuts and DFs are a matrix of important bioactive compounds such as Vitamins (Vitamin E, niacin , choline and/or folic acid), minerals (magnesium, potassium, calcium and/or phosphorus), phenolic compounds,
Select Disease Character Offset Disease Term Instance
diabetes mellitus 26455 of 1,650 particpants who were otherwise healthy or had dyslipidaemia, metabolic syndrome or type 2 diabetes mellitus showed that the consumption of tree nuts led to modest decreases in fasting blood glucose compared with
hyperglycemia 15191 platelets [[55]]. These results were extended using a wine grape powder supplementation, which prevented hyperglycemia and IR, and reduced oxidative stress in a rat model of metabolic syndrome (MetS) [[56]].Specific compounds
hyperglycemia 36551 in IR development [[124]]. In fact, kidneys lose the ability to retain magnesium in periods of acute hyperglycemia . It is excreted in the urine, leading to low mineral blood levels. It has been shown that correcting
hyperglycemia 59987 almonds12 units of dry-roasted almondsA low-calorie almond preload “appetizer” decreased postprandial hyperglycemia .Age is shown as mean ± SD unless otherwise stated. BMI, body mass index; CHO, carbohydrate; GLP-1,
hyperinsulinemia 19399 chronic clinical trials. Acute studies mostly demonstrate a decrease in postprandial glycaemia and hyperinsulinemia after nut consumption. In contrast, chronic randomized clinical trials designed to analyze the effects
hyperlipidemia 23739 insulin index. In contrast, in a crossover study conducted in 20 Chinese patients with T2D and mild- hyperlipidemia assigned to either a control diet (National Cholesterol Education Program (NCEP) step II diet) or an
metabolic syndrome 856 associated with the prevention and/or the management of such metabolic conditions as type 2 diabetes (T2D), metabolic syndrome and cardiovascular diseases. Several previous reviews of epidemiological studies and clinical trials
metabolic syndrome 15260 supplementation, which prevented hyperglycemia and IR, and reduced oxidative stress in a rat model of metabolic syndrome (MetS) [[56]].Specific compounds found in both nuts and DFs were also further investigated. Quercetin
metabolic syndrome 26426 including 25 trials with a total of 1,650 particpants who were otherwise healthy or had dyslipidaemia, metabolic syndrome or type 2 diabetes mellitus showed that the consumption of tree nuts led to modest decreases in fasting
metabolic syndrome 60258 IAUC, incremental area under the curve; IGT, impaired glucose tolerance; LPS, lipopolysaccharide; MetS, metabolic syndrome ; M/F, male/female; Ob, obese; Ow, overweight; RGR, relative glycaemic responses; T2D, type 2 diabetes;
obesity 15506 plant polyphenols which have showed a significant reduction of IR and inflammation associated with obesity . Eid et al. showed that quercetin (isolated from lingonberry) exerted an anti-diabetic activity by stimulating
obesity 33148 provides a strong rationale for its therapeutic potential in the nutritional management of T2D and obesity [[126]].Overall fiber contained in nuts and DFs is also able to decrease postprandial glycaemic levels
type 2 diabetes mellitus 26448 a total of 1,650 particpants who were otherwise healthy or had dyslipidaemia, metabolic syndrome or type 2 diabetes mellitus showed that the consumption of tree nuts led to modest decreases in fasting blood glucose compared with

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