Effect of High Glucose Levels on White Adipose Cells and Adipokines-Fuel for the Fire.

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dexamethasone 1 endocrinologydiseasesdrugs
hyperglycemia 1 endocrinologydiseases
obesity 3 endocrinologydiseases
Insulin 1 endocrinologydiseasesdrugs

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Insulin 1340 energy can be safely stored as an endogenous fuel until metabolic demand requires it to be released. Insulin levels are low in the fasting state, and rise in the post-prandial period. Counter-regulatory hormones,
dexamethasone 10255 differentiation. However, the experiments were performed in the absence of the usual adipogenic inducers ( dexamethasone , isobutylmethylxanthine, and insulin/insulin-like growth factor 1), and as a consequence, the overall
Select Disease Character Offset Disease Term Instance
hyperglycemia 787 resistance. When pancreatic islet β cells can no longer compensate, the blood glucose concentration rises ( hyperglycemia ), resulting in type 2 diabetes. Hyperglycaemia may further aggravate adipose cell dysfunction in ~90%
obesity 585 5/2017AbstractWhite adipocytes release adipokines that influence metabolic and vascular health. Hypertrophic obesity is associated with adipose tissue malfunctioning, leading to inflammation and insulin resistance. When
obesity 3600 hypertrophy and become dysfunctional, exhibiting inflammation and insulin resistance [[7],[8]].Overweight/ obesity with adipose hypertrophy increases the risk of developing type 2 diabetes. Indeed, a large majority
obesity 6727 normally protective for cell survival, is excessively up-regulated in adipose tissue in the setting of obesity and type 2 diabetes [[18]]. This maladaptive response is associated with increased apoptotic markers.Therefore,

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