Etiologic effects and optimal intakes of foods and nutrients for risk of cardiovascular diseases and diabetes: Systematic reviews and meta-analyses from the Nutrition and Chronic Diseases Expert Group (NutriCoDE)

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Term Occurence Count Dictionary
diabetes mellitus 6 endocrinologydiseases
obesity 2 endocrinologydiseases
type 2 diabetes mellitus 1 endocrinologydiseases

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Select Drug Character Offset Drug Term Instance
Select Disease Character Offset Disease Term Instance
diabetes mellitus 26578 additional specificity within the set of cardiometabolic outcomes (coronary heart disease (CHD), stroke, diabetes mellitus ). Analogy: based on the effects of similar factors on the disease outcome; see detailed footnotes below.
diabetes mellitus 28186 both CHD and weight gain.11 Based on analogies to other poor-quality carbohydrates in relation to both diabetes mellitus and weight gain.12 Based on analogies to vegetable oils in relation to CHD and cardiovascular risk factors.13
diabetes mellitus 28589 fruits, and vegetables.16 Based on analogies to other higher-quality carbohydrates in relation to both diabetes mellitus and weight gain.17 Based on analogies to other poor-quality carbohydrates in relation to diabetes mellitus,
diabetes mellitus 28696 diabetes mellitus and weight gain.17 Based on analogies to other poor-quality carbohydrates in relation to diabetes mellitus , and diabetes as a risk factor for stroke.18 Based on analogies to other lifestyle-related and nonlifestyle-related
diabetes mellitus 28977 in sodium (e.g., processed meats).19 Based on analogies to potassium.20 Based on insulin resistance/ diabetes mellitus pathways.21 Several individual studies show dose response; no published dose-response meta-analyses.22
diabetes mellitus 31870 mg/d.10.1371/journal.pone.0175149.t003Table 3Estimates of etiologic effects of dietary factors and risk of cardiovascular diseases and type 2 diabetes mellitus 1.Dietary FactorOutcomeStudies in Each Meta-analysis2SourceNo. of SubjectsNo. of EventsUnit of RR3RR
obesity 8175 For sodium and sugar-sweetened beverages (SSBs), we also reviewed effects on blood pressure (BP) and obesity , respectively, based on RCTs demonstrating primary effects on these risk pathways. Our detailed protocol
obesity 38966 did not identify sufficient evidence for effect modification by other factors beyond age, e.g. race, obesity , or overall diet quality.4 Excluding 100% juices.5 All four of these de novo meta-analyses were performed
type 2 diabetes mellitus 31863 mg/d.10.1371/journal.pone.0175149.t003Table 3Estimates of etiologic effects of dietary factors and risk of cardiovascular diseases and type 2 diabetes mellitus 1.Dietary FactorOutcomeStudies in Each Meta-analysis2SourceNo. of SubjectsNo. of EventsUnit of RR3RR

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