Incidence and prevalence of type 2 diabetes mellitus with HIV infection in Africa: a systematic review and meta-analysis.

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type 2 diabetes mellitus 7 endocrinologydiseases
diabetes mellitus 8 endocrinologydiseases
lipodystrophy 2 endocrinologydiseases
obesity 2 endocrinologydiseases

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diabetes mellitus 50 Title: BMJ OpenIncidence and prevalence of type 2 diabetes mellitus with HIV infection in Africa: a systematic review and meta-analysisA PrioreschiR J MunthaliL SoepnelJ
diabetes mellitus 611 3/2017AbstractObjectivesThis systematic review aims to investigate the incidence and prevalence of type 2 diabetes mellitus (T2DM) in patients with HIV infection in African populations.SettingOnly studies reporting data from
diabetes mellitus 2716 systematic review of the literature examining associations between HIV infection and treatment with type 2 diabetes mellitus (T2DM) incidence and prevalence in Africa.The stringent inclusion criteria used is a strength of this
diabetes mellitus 3547 itself,[2] and treatments used to combat HIV, are associated with metabolic complications.[3]Type 2 diabetes mellitus (T2DM) is one such disease that is becoming increasingly common, specifically in Africa due to rapidly
diabetes mellitus 15259 Cholesterol Education Programme; NNRTI, non-nucleotide reverse transcriptase inhibitors; T2DM, type 2 diabetes mellitus .Figure 3Incidence rates of T2DM in HIV-infected and treated participants in Africa. T2DM, type 2 diabetes
diabetes mellitus 15375 mellitus.Figure 3Incidence rates of T2DM in HIV-infected and treated participants in Africa. T2DM, type 2 diabetes mellitus .Prevalence of T2DM in HIV-infected compared with uninfected participantsTable 3 shows the data for
diabetes mellitus 18702 Federation.Figure 4Meta-analysis of studies comparing T2DM in HIV-infected and HIV-uninfected participants. T2DM, type 2 diabetes mellitus .Prevalence of T2DM in HIV-infected treated compared with untreated participantsTable 4 shows the data
diabetes mellitus 19894 5.Figure 5Meta-analysis of studies comparing T2DM in HIV-infected treated and untreated participants. T2DM, type 2 diabetes mellitus .DiscussionThis systematic review and meta-analysis of African studies showed no statistically significant
lipodystrophy 4202 response to HIV infection despite treatment,[6][7] antiretroviral drug-induced mitochondrial dysfunction, lipodystrophy and comorbidities.[5] Conversely, some studies have shown a decreased incidence of T2DM in HIV-infected
lipodystrophy 22148 (conversely, treatment with ritonavir and nevirapine decreased risk of T2DM). Interestingly, controlling for lipodystrophy did not modify this relationship and a direct effect of treatment on mitochondrial toxicity was thus
obesity 3870 and it is predicted that this will increase to 23.9 million by 2030. Besides associations with age, obesity , sex and race,[5] recent studies have associated T2DM with HIV infection, and with cART.[1][3][5] The
obesity 8130 duration of cART treatment, method of T2DM diagnosis, incidence of known risk factors for T2DM such as obesity , treatment provided for T2DM, incidence of T2DM in the control group and group with HIV and/or antiretroviral
type 2 diabetes mellitus 43 Title: BMJ OpenIncidence and prevalence of type 2 diabetes mellitus with HIV infection in Africa: a systematic review and meta-analysisA PrioreschiR J MunthaliL SoepnelJ
type 2 diabetes mellitus 604 3/2017AbstractObjectivesThis systematic review aims to investigate the incidence and prevalence of type 2 diabetes mellitus (T2DM) in patients with HIV infection in African populations.SettingOnly studies reporting data from
type 2 diabetes mellitus 2709 systematic review of the literature examining associations between HIV infection and treatment with type 2 diabetes mellitus (T2DM) incidence and prevalence in Africa.The stringent inclusion criteria used is a strength of this
type 2 diabetes mellitus 15252 National Cholesterol Education Programme; NNRTI, non-nucleotide reverse transcriptase inhibitors; T2DM, type 2 diabetes mellitus .Figure 3Incidence rates of T2DM in HIV-infected and treated participants in Africa. T2DM, type 2 diabetes
type 2 diabetes mellitus 15368 mellitus.Figure 3Incidence rates of T2DM in HIV-infected and treated participants in Africa. T2DM, type 2 diabetes mellitus .Prevalence of T2DM in HIV-infected compared with uninfected participantsTable 3 shows the data for
type 2 diabetes mellitus 18695 Federation.Figure 4Meta-analysis of studies comparing T2DM in HIV-infected and HIV-uninfected participants. T2DM, type 2 diabetes mellitus .Prevalence of T2DM in HIV-infected treated compared with untreated participantsTable 4 shows the data
type 2 diabetes mellitus 19887 5.Figure 5Meta-analysis of studies comparing T2DM in HIV-infected treated and untreated participants. T2DM, type 2 diabetes mellitus .DiscussionThis systematic review and meta-analysis of African studies showed no statistically significant

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